Description:
Regression ensemble of sensillum SBT-II-B with 4 individual models (I9, I12, I18, and I20) used for prediction of spike amplitude of the extracellularly record of ORN response potentials of the antennal trichoid
sensilla to Cx. quinquefasciatus repellents.
The training was performed with the Bagging algorithm as default in Weka 3.9.4 with a 10-fold cross-validation with the SMOreg classifier (with Pearson Universal Kernel (PUK)). Models I9, I12, I18, and I20 were
developed by using 3, 3, 6, and 4 QuBiLS-MIDAS descriptors, respectively, namely:
HM_Q_AB_nCi_2_M10_SS5_T_LGP[2]_e_MID
ES_S_F_AB_nCi_2_M12_MP7_n_T_LGP[5]_a_MID
GM_Q_AB_nCi_2_M1_SS4_T_LGP[2]_e_MID
Q3_B_AB_nCi_2_M11_MP3_o_T_LGL[2-3]_v-s_MID
AC[2]_K_B_AB_nCi_2_M3_NS0_n_T_LGP[2]_e-p_MID
MN_Q_AB_nCi_2_M1_MP2_T_LGP[2]_s_MID
Q1_Q_AB_nCi_2_M8_NS7_T_LGL[2-3]_h_MID
Q2_B_AB_nCi_2_M11_MP3_o_T_LGL[2-3]_v-s_MID
AC[2]_S_B_AB_nCi_2_M5_NS6_T_LGL[1-2]_m-h_MID
Training set:
50 compounds extracted from the Liu, et al., 2013 original experimental research constitute the training set 10.1016/j.jinsphys.2013.08.016
Performance:
For a 10-fold cross-validation, the statistical parameters (performance without applicability domain) are R = 0.9957, MAE = 2.9198, RMSE = 4.7586, RAE = 7.5054 %, and RRSE = 9.3483 %.
Classification Breakpoint:
The breakpoint for sensillum SBT-II-B is 32.8 spikes/s. Values greater than or equal to the breakpoint will elicit a response in this specific sensillum. Lower values represent certain actions occurring, however,
they are not enough to activate the sensillum response.
Reference:
Liu et al. Olfactory responses of the antennal trichoid sensilla to chemical repellents in the mosquito, Culex quinquefasciatus. 2013, 59(11), 1169-1177.
DOI: 10.1016/j.jinsphys.2013.08.016