Description:
Regression model of sensillum SBT-I-B with 6 QuBiLS-MIDAS descriptors used for prediction of spike amplitude of the extracellularly record of ORN response potentials of the antennal trichoid sensilla to Cx. quinquefasciatus repellents.

The training was performed with Vote algorithm as default in Weka 3.9.4 with a 10-fold cross-validation using a combination of the average of probabilities (agglomeration rule) of Gaussian Processes and SMOreg (both with Pearson Universal Kernel (PUK)), and IBk (with K-nearest neighbours = 10 and True cross-validation). The 6 QuBiLS-MIDAS descriptors are namely:

K_B_AB_nCi_2_M11_SS7_o_T_LGL[1-2]_a-p_MID
S_F_AB_nCi_2_M14_NS2_n_T_LGL[2-3]_c_MID
MX_Q_AB_nCi_2_M8_SS3_T_LGP[2]_v_MID
ES_RA_F_AB_nCi_2_M16_MP2_T_LGL[5-6]_s_MID
AC[1]_S_B_AB_nCi_2_M5_NS6_T_LGP[2]_e-p_MID
HM_Q_AB_nCi_2_M12_SS4_T_LGP[5]_p_MID

Training set:
50 compounds extracted from the Liu, et al., 2013 original experimental research constitute the training set 10.1016/j.jinsphys.2013.08.016

Performance:
For a 10-fold cross-validation, the statistical parameters (performance without applicability domain) are R = 0.9213, MAE = 8.2697, RMSE = 10.7981, RAE = 53.1897 %, and RRSE = 40.6238%.

Classification Breakpoint:
The breakpoint for sensillum SBT-I-B is 16.3 spikes/s. Values greater than or equal to the breakpoint will elicit a response in this specific sensillum. Lower values represent certain actions occurring, however, they are not enough to activate the sensillum response.

Reference:
Liu et al. Olfactory responses of the antennal trichoid sensilla to chemical repellents in the mosquito, Culex quinquefasciatus. 2013, 59(11), 1169-1177. DOI: 10.1016/j.jinsphys.2013.08.016