Regression ensemble model based on three individual models to predict the run time (in minutes) that a molecule will spend for docking with one protein. The average of the three individual models will be the output of the estimated time. The models were developed by using 5 individual descriptors calculated with CDK descriptor calculator, namely: nAtom, nHBDon, TopoPSA, XLogP, nRotB, which correspond to the number of atoms, number of H-Atoms as Donors, Topological Polar Surface Area, partition coefficient, and number of Rotatable bonds, respectively. The predicted run time is compared with the one specified, and if the former is less than the latter then molecule is docked, otherwise, molecule is not docked.